Ricin (a toxic protein from the seeds of Ricinus communis) is a powerful inhibitorof the poly(U)-directed incorporation of phenylalanine into polypeptides catalysed by isolated rat liver ribosomes and elongation factors 1 and 2 (EF 1 and EF 2). ... No added cofactor is necessary for the inhibitory action of the toxin.
Proteins can be used in a wide variety of applications such as the development of functional assays, screening small-molecules for target binding, receptor activation of signal-transduction pathways in-situ, or simply for use as Western Blot controls. We offer native protein extracts as well as engineered recombinant proteins in the form of cell lysates or highly-purified reagents.
Recombinant proteins are generated in bacterial, mammalian, or insect expression systems and often contain common expression tags, such as His, Myc, or TAT. Many are also validated as being bio-active, making them ideal for use in functional assays. Each bio-active protein is tested to assure functionality and evaluated to certify that they contain low levels of endotoxin.